Yun-Wei Chiang

	Education
	PhD, Cornell University (2006) MS, Cornell University (2001) BS, National Sun Yat-sen University (1998)
	Professional Experience
	2017 ~	Professor of NTHU
	2021 ~ 2024	Professor of NTHU & Chairman
	2015 ~ 2021	Professor of NTHU & Vice-Chairman
	2012 ~ 2017	Associate Professor of NTHU
	2007 ~ 2012	Assistant Professor of NTHU
	2006 ~ 2007	Postdoctoral Research, Cornell University
	Research Interest
	Physical Chemistry, Biophysical Chemistry, Electron Spin Resonance, Nano-biology, Water Dynamics.

Select Publications

A. Biophysics/Apoptosis/Membrane Proteins

C.C. Cheng, R.F. Tsai, C.K. Lin, K.T. Tan, V. Kalendra, M. Simenas, C.W. Lin*, and Y.W. Chiang*, In-Cell DEER Spectroscopy of Nanodisc-Delivered Membrane Proteins in Living Cell Membranes, JACS Au, 4 (2024) 3766-3770.

P.S. Yeh, C.C. Li, Y.S. Lu, and Y.W. Chiang*, Structural Insights into the Binding and Degradation Mechanisms of Protoporphyrin IX by the Translocator Protein TSPO, JACS Au, 3 (2023) 2918-2929.

D T.-W. Wang, T. Y.-C. Tang, C.T. Kuo, Y.T. Yu, E. H.-L. Chen, M.T. Lee, R.F. Tsai, H.Y. Chen, Y.W. Chiang*, and R. P.-Y. Chen*, Cholesterol Twists the Transmembrane Di-Gly Region of Amyloid-Precursor Protein, PNAS Nexus, 2 (2023) 162.


	A4	C.L. Hung, H.H. Chang, S.W. Lee, Y.W. Chiang, Stepwise activation of the pro-apoptotic protein Bid at mitochondrial membranes, Cell Death & Differentiation*, 28 (2021) 1910-1925.

C.C.Li, T.Y.Kao, C.C.Cheng, Y.W. Chiang*, Structure and regulation of the BsYetJ calcium channel in lipid nanodiscs, Proceedings of the National Academy of Sciences (PNAS), 117 (2020). 30126-30134.

Y.J. Lan, P.S. Yeh, T.Y. Kao, Y.C. Lo, S.C. Sue, Y.W. Chen, D.W. Hwang*, Y.W. Chiang*, Anti-apoptotic BCL-2 regulation by changes in dynamics of its long unstructured loop, Communications Biology, 3 (2020) 668.

R.F. Tsai, N.C. Lin, T.Y. Kao, Y.H. Kuo, F.C. Lo, W.F. Liaw, Y.W. Chiang*, Nitrosylation of the Diiron Core Mediated by the N Domain of YtfE, Journal of Physical Chemistry Letters, 11 (2020) 8538-8542.

Y.C. Lai, C.C. Li, T.C. Sung, C.W. Chang, Y.J. Lan, and Y.W. Chiang*, The Role of Cardiolipin in Promoting the Membrane Pore-forming Activity of BAX Oligomers, BBA Biomembranes, 1861 (2019) 268-280.

B. Physical Chemistry/Water Dynamics/ESR Simulations

T.Y. Kao and Y.W. Chiang*, DEERefiner-assisted Structural Refinement Using Pulsed Dipolar Spectroscopy: A Study on Multidrug Transporter LmrP, Physical Chemistry Chemical Physics, 25 (2023) 24508-24517.

P.S. Ho, T.Y. Kao, C.C. Li, Y.J. Lan, Y.C. Lai, and Y.W. Chiang*, Nanodisc Lipids Exhibit Singular Behaviors Implying Critical Phenomena, Langmuir, 38 (2022) 15372-15383.

T.Y. Kao, C.L. Hung, Y.J. Lan, S.W. Lee, and Y.W. Chiang*, A Simple Cryoprotectant-Free Method To Advance
Pulsed Dipolar ESR Spectroscopy for Capturing Protein Conformational Ensembles, The Journal of
Physical Chemistry B, 126 (2022) 423-429.

Y.C. Lai, Y.H. Kuo, and Y.W. Chiang*, Identifying Protein Conformational Dynamics Using Spin‐label ESR, Chemistry - An Asian Journal, 14 (2019) 3981-3991.

Y.H. Kuo and Y.W. Chiang*, Slow Dynamics around a Protein and Its Coupling to Solvent, ACS Central Science, 4 (2018) 645-655.

K.J. Chang⁺, Y.H. Kuo⁺, and Y.W. Chiang*, Study of Protein Dynamics under Nanoconfinement by Spin-Label ESR: A Case of T4 Lysozyme Protein, Journal of Physical Chemistry B, 121 (2017) 4355–4363.

T.Y. Kao, C.J. Tsai, Y.J. Lan, andY.W. Chiang*, Role of Conformational Heterogeneity in Regulating the Apoptotic Activity of BAX Protein,Physical Chemistry Chemical Physics, 19 (2017) 9584-9591.

YW Huang, YC Lai, CJ Tsai, and YW Chiang*, Mesopores Provide an Amorphous State Suitable for Studying Biomolecular Structure at Cryogenic Temperatures, Proceedings of the National Academy of Sciences (PNAS), 108 (2011) 14145-14150.

C. Inorganic/Materials

S.Y. Fu, C.H. Chang, A.S. Ivanov, I. Popovs, J.L. Chen, Y.F. Liao, H.K. Liu, S. Chirra, Y.W. Chiang, J.C. Lee, W.L.
Liu, W. Kaveevivitchai*, T.H. Chen*, Mixed-Valence CuI/CuIII Metal−Organic Frameworks with Non-
innocent Ligand for Multielectron Transfer, Angew. Chem. Int. Ed., (2023) e202312494.

C. Maitra, P.D. Jadhav, D. Barik, Y.S. Ho, C.C. Cheng, M.J. Cheng*, Y.W. Chiang*, and R.S. Liu*, Nitrosoarenes
Implement Cascade Cyclization of 1-Allenyl-2-alkynylbenzenes Through Diradical Mechanism, Organic
Letters, 25 (2023) 82-86.

Y.Y. Wu, J.C. Hong, R.F. Tsai, H.R. Pan, B.H. Huang, Y.W. Chiang, G.H. Lee, M.J. Cheng,* and H.F. Hsu*, Ligand-Based Reactivity of Oxygenation and Alkylation in CobaltComplexes Binding with (Thiolato)phosphine Derivatives, Inorganic Chemistry, 59 (2020) 4650-4660.

P. Dai*, Q. Wang, M. Xiang, T.M. Chen, X. Zhang, Y.W. Chiang, T.S. Chan, X. Wang*, Composition-Driven Anionic Disorder-Order Transformations Triggered Single-Eu2+-Converted High-Color-Rendering White-Light Phosphors, Chemical Engineering Journal, 380 (2020) 122508.

C.H. Ke, C.H. Chen, M.L. Tsai, H.C. Wang, F.T. Tsai,Y.W. Chiang, W.C. Shih, D.S. Bohle, and W.F. Liaw*{Fe(NO)2}9 Dinitrosyl Iron Complex Acting as a Vehicle for the NO Radical, Journal of the American Chemical Society, 139 (2017) 67-70.

C.C. Wang, H.C. Chang, Y.C. Lai, H. Fang, C.C. Li, H.K. Hsu, Z.Y. Li, T.S. Lin, T.S. Kuo, F. Neese, S. Ye*,Y.W.
Chiang*, M.L. Tsai*, W.F. Liaw*, and W.Z. Lee*, A Structurally Characterized Nonheme Cobalt-Hydroperoxo
Complex Derived from its Superoxo Intermediate via Hydrogen Atom Abstraction, Journal of the
American Chemical Society, 138 (2016) 14186-14189.

Full publication list ==> (Link)

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