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Yu, Chin -2

Title： Professor

Education：

Florida State University(USA)(Ph.D.) (1984)
Fu-Jen Catholic University(B.S.) (1976)
Office： Chemistry Building R209
Phone number： 33353
E-mail： cyu.nthu@gmail.com
Web site： http://cyucv.meworks.cc
http://my.nthu.edu.tw/~chem/course/cyunmr/NMR.htm

Work Experience：

1992 ~
1985 ~ 1992
1984 ~ 1985
Professor of NTHU
Associate Professor of NTHU
Postdoctoral Research, University of California,Davis

Research Areas：

NMR; Biochemistry; Protein Engineering and Molecular Modeling


Journal Articles：
  1. Mohan SM and *Yu C."The IL1α-S100A13 hetero-tertrammeric complex structure:A Component in the non-classical pathway for Interleukin 1α(IL1α) secretion",J.Biol. Chem. ,2011,accepted.
     
  2. Wang HM, Yu C. “Investigation of the refolding pathway of human acidic fibroblast growth factor from the residual structure obtained by denatured state hydrogen/deuterium exchange”Biophys. J. ,2011,accepted.
     
  3. Kumar SM, Wang HM, Mohan SK, Chou RH, Yu C. “Solution structure of human acidic fibroblast grow factor in complex with inositol hexaphosphate, an anti-angiogenic agent”Biochemistry,2010 ,49,10756-10764.
     
  4. Huang HW,Mohan SK, *Yu C."The NMR solutiion structure of human epidermal growth factor at physiological pH", Bioachem. Biophys. Res. Commu, 2010, 420, 705-710
     
  5. Rani SG, Mohan SK , Yu C. “Molecular level interactions of S100A13 with amlexanox: inhibitor for the formation of multi-protein complex in non-classical pathway of acidic fibroblast factor”,Biochemistry, 2010, 49, 2585-2593.
     
  6. Chang HK, Mohan SK, Yu C. “1H, 13C and 15N backbone and side chain resonance assignments of human Interleukin 1A”, J. Biomol. NMR Assign., 2010, 4, 59-60.
     
  7. Mohan SK, Rani SG, Yu C. “The FGF1-S100A13-C2A hetero-hexameric complex structure: A component in the non-classical pathway for FGF1 secretion”, J. Biol. Chem., 2010, 285, 15464-75.
     
  8. Anbazhagan V, Wang HM, Lu  CS, Yu, C. “A residue-level investigation of the equilibrium unfolding of C2A domain of synaptotagmin 1” Arch. Biochem. Biophys., 2009, 490, 158-162.
     
  9. Mohan SK, Rani SG, Kumar, SM, Yu C. “S100A13-C2A binary complex structure—a key component in the acidic fibroblast growth factor for the non-classical pathway” Biochem. Biophys. Res. Commu., 2009, 380, 514-519.
     
  10. Shanmuganathan A, Kumar T. K. S., Huang, C. M., Yu. C., Chin, D. H. “A superior drug carrier- aponeocarzinostatin in partially unfolded state fully protects the labile antitumor enediyne” J. Biomed. Sci., 2009, 26, 48-59.
     
  11. Kandaswamy J, Hariharan P, Kumar TK, Yu C, Lu TJ, Chin DH.“Is association of labile enediyne chromophore a mutually assured protection for carrier protein?Anal. Biochem., 2008, 381(1):18-26. ”  
     
  12. Kathir KM, Rajalingam D, Sivaraja V, Kight A, Goforth RL, Yu C, Henry R, Kumar TK. “Assembly of chloroplast signal recognition particle involves structural rearrangement in cpSRP43”J. Mol. Biol., 2008, 381(1):49-60.
     
  13. Kathir KM, Ibrahim K, Rajalingam D, Prudovsky I, Yu C, Kumar TK.”S100A13-lipid interactions-role in the non-classical release of the acidic  fibroblast growth factor”.Biochim Biophys Acta.,2007, 1768(12):3080-9.
     
  14. Rajalingam, Dakshinamurthy; Graziani, Irene; Prudovsky, Igor; Yu, Chin; Kumar, Thallapuranam Krishnaswamy S. “Relevance of Partially Structured States in the Non-Classical Secretion of Acidic Fibroblast Growth Factor”     Biochemistry, 2007, 46(32), 9225-9238.
     
  15. Snake Venom Research: Dedicated to the Memory of Prof. C.-C. Yang. [In: Toxin Rev., 26(2)]. Yu, Chin; Editor. USA., 2007, 134 pp. Publisher: (Informa Healthcare, New York, N. Y.)
     
  16. Ghule, Anil Vithal; Kathir, Karuppanan Muthusamy; Suresh Kumar, Thallapuranam Krishnaswamy; Tzing, Shin-Hwa; Chang, Jia-Yaw; Yu, Chin; Ling, Yong-Chien. “Carbon nanotubes prevent 2,2,2 trifluoroethanol induced aggregation of protein”, Carbon, 2007, 45(7), 1586-1589.
     
  17. Veerappan Anbazhagan, Pamanji Sudhakar Reddy, Chin Yu, “Cardiotoxin from Taiwan cobra (naja naja atra): Structure, dynamics, interaction and protein folding”, Toxin Reviews, 2007, 26 (2), 203-229.
     
  18. Sepuru Krishna Mohan and Chin Yu. “Structure fuctional relationship of Cobrotoxin, naja naja atra”, Toxin Reviews, 2007, 26 (2), 99-122.
     
  19. Vaithiyalingam Sivaraja, Thallapuranam Krishnaswamy Suresh Kumar, Igor  Prudovsky and Chin Yu.  “Copper Binding Affinity of S100A13, a Key  Component of the FGF-1 Non-Classical Copper-Dependent Release Complex",  2006, Biophys. J., 91, 1832-43.
     
  20. Graziani I, Bagala C, Duarte M, Soldi R, Kolev V, Tarantini F, Kumar TK, Doyle A, Neivandt D, Yu C, Maciag T, “Release of FGF1 and p40  synaptotagmin-1 correlates with their membrane destabilizing ability”,  2006, Biochem. Biophys, Res. Commun., 349, 192-9.
     
  21. Hui-Chu Hsieh, T.K.S. Kumar, D. Siveraman, C. Yu. “Refolding of a Small All Beta-Sheet Protein Proceeds with Accumulation of Kinetic Intermediates Archives of Biochemistry and Biophysics”, 2006, Arch. Biochem. Biophys., 447, 147-154.
     
  22. Chang, J. Y. Lu, B. Y., Lin, C. C. and Yu, C. “Fully Oxidized Scrambled Isomers Are Essential and Predominant Folding Intermediates of Cardiotoxin-III”, 2006, Febs Lett., 580, 656-660.
     
  23. Karuppanan Muthusamy Kathir, Thallapuranam Krishnaswamy S. Kumar and Chin Yu. “Understanding the Mechanism of the Anti-mitogenic Activity of Suramin”, 2006, Biochemistry,24, 899-906.
     

 

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